Open Positions

Research Associate

Will participate in studies examining the role of immune cells in diseases of the central nervous system, including neurodegenerative disorders and cancers. The Fraenkel lab is using omic measurements and computational modeling to reveal the molecular mechanisms behind neurodegenerative diseases and brain tumors to identify novel potential therapeutic strategies and to test these strategies in vitro and in vivo.

Will generate and analyze cell imaging data relevant to these studies. The work will involve the design and execution of imaging experiments using methods such as CycIF and CODEX and basic computational processing. It will require close teamwork with the lab in-house computational scientists and with external collaborators.

Job Requirements:

REQUIRED: master’s degree in biological or biomedical engineering with a background in molecular neuroscience; at least three years of relevant research experience; proven experience with histological assays such as immunohistochemistry and immunofluorescence in tissue and cell culture; strong organizational, communication, and planning skills; and ability to work in coordination and collaboration with multiple research groups.

PREFERRED: experience with CycIF and/or CODEX and experience performing collaborative work with data scientists and systems biologists.

The position may require working nights and weekends. Some domestic travel may also be required.

Technical Associate I

Will participate in studies examining the role of immune cells in diseases of the central nervous system, including neurodegenerative disorders and cancers. The lab uses omic measurements and computational modeling to reveal the molecular mechanisms behind neurodegenerative diseases and brain tumors to identify novel potential therapeutic strategies and to test these strategies in vitro and in vivo.

Will participate in generating and analyzing cell imaging data relevant to these studies. The work will involve assisting with the design and execution of imaging experiments using methods such as CycIF and CODEX and basic computational processing. It will require close teamwork with the lab in-house computational scientists and with external collaborators. Principal responsibilities include collecting imaging data using methods that include CycIF, CODEX, or related technologies; identifying and testing antibodies for these studies; assisting the computational team with analyzing data, developing biological hypothesis, and designing follow-up experiments; conducting follow up experiments based on the proposed hypothesis; and communicating and coordinating the research with collaborators.

Job Requirements:

REQUIRED: a bachelor’s degree in biological or biomedical engineering with a background in molecular neuroscience; at least two years of relevant research experience; proven experience with histological assays such as immunohistochemistry and immunofluorescence in tissue and cell culture; strong organizational, planning skills, and communication skills; and ability to work in coordination and collaboration with multiple research groups.

PREFERRED: experience with CycIF and/or CODEX and experience in collaborative work with data scientists and systems biologists.

Postdoctoral, predoctoral, UROP and technical positions available.

We are looking for highly motivated candidates to participate in experimental and computational projects studying several human diseases using Systems Biology techniques. We obtain diverse data from ChIP-Seq, RNA-Seq, ATAC-Seq, WGS, reverse genetics and phospho-proteomics. We analyze these data to identify altered regulatory and signaling networks. Highly motivated applicants trained in either experimental or computational methods are welcome to apply.

Interested candidates should write to apply.fraenkel “AT” mit “DOT” edu

A note to prospective graduate students who have not yet been admitted to MIT:

At MIT students are admitted by graduate programs, not by individual faculty members. If you would like to learn more about the various graduate programs at MIT, including Biological Engineering and CSB, please feel free to contact me. However, it will not have any impact on your chances of admission to the programs.